Number needed to treat for statin therapy
Web27 okt. 2013 · There is a great website that analyzes data from multiple studies to estimate the number of patients needed to treat in order to help and/or harm a patient. Two such … WebThe absolute reductions in risk and the numbers needed to treat were determined from five-year Kaplan ... Editorial Stroke — An Equal Opportunity for the Initiation of Statin …
Number needed to treat for statin therapy
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Web10 okt. 2015 · Targeting statin therapy. The large reduction of age-related deaths is the main factor responsible for the rapid increase in the number of very elderly, and it is in … Web1 nov. 2024 · Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol …
WebThis is approximately equivalent to the potential impact of risk‐targeted therapy at a treatment threshold of 5% 10‐year atherosclerotic cardiovascular disease risk (5.6% impact [4.7–6.6]). Whereas the estimated maximum NNT 10 is much improved for benefit‐targeted versus risk‐targeted therapy at these equivalent‐impact thresholds (43.5 vs 180), the … Web6 nov. 2024 · For those with a CAC score above 100, just 12 patients would need to be treated to prevent an event. Shaking Up Risk Assessments The current guidelines recommend starting moderate- to high-intensity statin therapy in patients ages 40 to 75 years without cardiovascular disease who have a 10-year ASCVD risk ≥ 7.5%.
WebConsider reducing the statin dose, or starting with the lowest possible dose. Monitor concurrent use and advise people to report any unexplained muscle pain, tenderness or … WebOn average, statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment. A greater benefit is observed with high-intensity statin therapy.
WebHomeCirculation: Cardiovascular Quality and OutcomesVol. 2, No. 6Number Needed to Treat With Rosuvastatin to Prevent First Cardiovascular Events and Death Among Men and Women With Low Low-Density Lipoprotein Cholesterol and Elevated High-Sensitivity C-Reactive Protein Free AccessResearch Article PDF/EPUB About View PDF View EPUB …
Web10 okt. 2015 · The NNT was thus (100/1.1) = 91, meaning that 91 high risk men in the west of Scotland, aged between 55 and 65 years with serum cholesterol greater than 6.5 mmol/L, needed to be treated (with pravastatin) for five years to prevent one death. gluten free slow cooker recipeWeb11 nov. 2024 · For some people, lifestyle changes, such as a healthier diet and more exercise, may prevent or treat unhealthy cholesterol levels. For others with high cholesterol, medication may also be needed. Work with … bold title llc huntsville alWebThey reported a similar number needed to treat (19) to prevent major cardiovascular complications (including death) in high-risk patients for perioperative β-blocker and statin therapy but cautioned against the potentially harmful adverse effects of β-blockers in patients with a lower risk for cardiovascular events. boldt island toursWebValues are the difference in MACE rates between control and statin-treated groups, which is equivalent to the absolute risk reduction and the number of cardiovascular events that are prevented per 100 people treated with a statin. aP < .05 between groups. Table 1. Characteristics of Included Studies View LargeDownload Table 2. bold title llcWebThe absolute reductions in risk and the numbers needed to treat were determined from five-year Kaplan ... Editorial Stroke — An Equal Opportunity for the Initiation of Statin Therapy D.M. Kent; gluten free smartiesWeb1 dec. 2024 · The 5-year number needed to treat (NNT) was 470 and 204 in the risk categories <5% and 5–7.4%, respectively, and 75 and 62 in the 7.5–9.9% category than in the 10–19.9% category, respectively. Statin therapy should remain a priority in patients at high 10-year CHD risk (10–19.9%). gluten free slow cooker meatballsWeb30 sep. 2003 · Statins provide a cardiovascular and total mortality benefit for patients with clinically evident occlusive vascular disease (secondary prevention) and a cholesterol of >3.5 mM. Large RCTs are required to test different statin dosing strategies for secondary prevention before making firm recommendations. RR = Relative Risk. gluten free slow cooker recipes easy