WebNew research suggests that doses ranging from 120mg/d to more than 700 mg/d, with correspondingly higher SMLs, may be optimal for many patients, and there does not appear to be a maximum daily dose limit when determining what is adequately "enough" methadone in MMT. 117 PDF View 9 excerpts, references background WebIn a randomized, controlled trial of 263 first-episode patients with no or limited prior exposure to antipsychotics that compared olanzapine (mean modal dose 9.1 mg/day) and haloperidol (mean modal dose 4.4 mg/day), the weight gain after 2 years of treatment for olanzapine was 10.2 kg using a last-observationcarried-forward analysis and 14 kg for observed cases.
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