Chemokine like factor
WebNov 8, 2024 · Chemokine-like factor 1 can also mediate chemotaxis via CCR4. We designed and synthetized novel CCR4 antagonists, which were piperazinyl pyridine derivatives, for disrupting the interaction... Studies conducted in freshly isolated cells, cultured cells, animals, and tissue samples indicate that CKLF1 is a chemokine -like chemotactic factor that acts through the CCR4 receptors on human CD4+ Th2 lymphocytes, neutrophils, monocytes, macrophages, dendritic cells, and perhaps other CCR4-receptor … See more Chemokine-like factor (CKLF) is a member of the CKLF-like MARVEL transmembrane domain-containing family of proteins that in humans is encoded by the CKLF gene. This gene is located on band 22.1 in the long (i.e. "q") arm See more Through the process of alternative splicing, the CKLF gene encodes 4 CKLF protein isoforms, i.e. proteins made from different areas of the same gene. These isoforms are 1) CKLF1 and … See more • Human CKLF genome location and CKLF gene details page in the UCSC Genome Browser. See more • Boudinot P, Salhi S, Blanco M, Benmansour A (July 2001). "Viral haemorrhagic septicaemia virus induces vig-2, a new interferon-responsive gene in rainbow trout". Fish … See more
Chemokine like factor
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Webpthr22776:sf45 chemokine-like factor 1 hit; pthr22776 marvel-containing potential lipid raft-associated protein 1 hit; prosite. view protein in prosite; ps51225 marvel 1 hit; mobidb. WebRecent studies have revealed that chemokine-like factor-like MARVEL transmembrane domain-containing family member 6 (CMTM6) promotes tumor progression and modulates tumor immunity by regulating programmed death-ligand 1 stability; however, its intrinsic functions and regulatory mechanisms in clear cell renal cell carcinoma (ccRCC) remain …
WebBackground: Chemokine-like factor 1 (CKLF1) was recently identified as a novel cytokine. The full-length CKLF1 cDNA contains 530 bp encoding 99 amino acid residues with a … WebJan 9, 2024 · Introduction: Chemokine-like factor (CKLF)-like MARVEL transmembrane domain containing 6 (CMTM6) is a protein localized to the cell membrane and is known for its ability to co-localize with PD-L1 on …
WebSep 22, 2024 · Gene ID: 152189, updated on 22-Sep-2024 Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. WebDec 6, 2024 · By screening databases for sequences that share homology with chemokine-like factor (CKLF; 616074 ), followed by RT-PCR of a prostate cDNA library, Han et al. (2003) cloned CKLFSF6. The deduced 183-amino acid CKLFSF6 protein has 4 transmembrane segments. It shares about 31% sequence identity with CKLFSF4 …
WebFeb 2, 2024 · Insulin-like growth factor 1 (IGF-1) is an endocrine and autocrine/paracrine growth factor that has pleiotropic effects on development, metabolism, cell differentiation, and survival. ... IGF-1 downregulates markers of systemic oxidative stress and decreases C-reactive protein and chemokine CXCL12. Markers of systemic oxidative stress (A and B ...
WebChemokine-like factor 1: A promising therapeutic target in human diseases. CKLF1, a recently identified chemokine, has been reported by a number of studies to play … how to unhide remote desktop barWebDec 23, 2024 · 2. Cell Death and Inflammation: A Road to HCC. HCC is the most prevalent primary liver cancer and the third most common cause of cancer death worldwide, with a 5-year survival of 18% [].HCC is closely associated with chronic inflammation and fibrosis, representing the common end-stage of CLD from excessive alcohol intake, viral … how to unhide printerWebApr 27, 2015 · Chemokine-like factor 1 (CKLF1) is a newly discovered cytokine which functions by engaging its receptor of C-C chemokine receptor 4 (CCR4) [ 11 ]. The full length of CKLF1 cDNA has been cloned from phytohaemagglutinin-stimulated U937 cells, and encodes ninety-nine amino residues [ 12 ]. how to unhide rhinoWebNov 1, 2024 · Chemokine (C-X-C motif) ligand 8 CXCR4 Chemokine (C-X-C motif) receptor 4 CKLF1 Chemokine-like factor 1 COX-2 Cyclooxygenase-2 CTL Cytotoxic T lymphocyte CSC Cancer stem cell CSCL Cancer stem cell-like CYLD Cylindromatosis lysine 63 deubiquitinase CRCSC Colorectal cancer stem cell ccRCC Clear cell renal cell … how to unhide processes in windows 7WebNov 27, 2024 · By screening databases for sequences that share homology with chemokine-like factor (CKLF; 616074 ), followed by RT-PCR of a spleen cDNA library, Han et al. (2003) cloned CKLFSF4. They also identified alternatively spliced forms of CKLFSF4. One variant encodes a 234-amino acid protein with 4 transmembrane segments. oregon dmv office locationWebJun 8, 2024 · This study aimed to examine the expression and clinical significance of chemokine-like factor-like MARVEL transmembrane domain-containing family member 8 (CMTM8) in gastric cancer (GC). The mRNA and protein expression of CMTM8 were detected by bioinformatics analysis and immunohistochemistry (IHC), respectively. … oregon dmv office locations and hoursWebSep 22, 2024 · Gene ID: 112616, updated on 13-May-2024 Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. how to unhide program data folder windows 10